Sensory feedback to investigate and drive cortical plasticity during phantom pain
Ali Asghar Zarei received his Bachelor's degree in Electronic Engineering from Sadjad University, Mashhad, Iran, in 2013, and his Master's degree in Biomedical Engineering from Amirkabir University, Tehran, Iran, in 2017.
Ali's project will be investigating the cortical plasticity during phantom pain following by sensorimotor interaction. Today the underlying mechanism of PLP is unknown, but modulation of cortical plasticity has shown to be correlated with onset and relief of PLP. To understand the effectiveness of sensory feedback, Ali has done his first PhD study to explore the cortical and perceptual responses following high-frequency electrical stimulation applied as surface electrical stimulation on healthy subjects. The focus of the PhD project is to investigate possible altered cortical responses following steady-state electrical stimulation in amputees and healthy subjects. This methodology may be beneficial for the design of possible therapies using sensory input to alleviate PLP. In this way, the effect of sensory feedback on PLP would be investigated by conducting experiments on amputees with PLP and comparing the results with healthy subjects' cortical activity.